JFX Health Online & Mental Health

The anticoagulant into the ESR tube standing vertically, red blood cells sink because the density is greatest. Usually the end of the first hour of red blood sinking in the distance that red blood cell sedimentation rate, called the erythrocyte sedimentation rate, or ESR.

The Erythrocyte Sedimentation Rate（ESR）is governed by the balance between pro-sedimentation factors, mainly fibrinogen, and those factors resisting sedimentation, namely the negative charge of the erythrocytes (zeta potential). When an inflammatory process is present, the high proportion of fibrinogen in the blood causes red blood cells to stick to each other. The red cells form stacks called ‘rouleaux’ which settle faster. Rouleaux formation can also occur in association with some lymphoproliferative disorders in which one or more immunoglobulins are secreted in high amounts. Rouleaux formation can, however, be a normal physiological finding in horses, cats and pigs.